ĮDIT : Longest supported does not necessarily equate with "best" or even good, IMHO. Have you tried the Audigy RX drivers ? AFAIK, it uses the same EMU chip as the Audigy 2ZS. Unless someone knows where to get WIn-10 drivers for this sound card ?
I will have to say this was the best sound Creative labs manufactured. These devices are end of life products according to Creative, drivers are still on Creatives website. These official drivers are only for Sound Blaster devices that run are attached to USB ports. Since this sound card was supported for such a long time. Sound Blaster Live Drivers for Windows 10. It was supported in Win98 thru Win-10 up until recently when Microsoft and Creative labs discontinued support in Win-10 The Sound Blaster Audigy 2zs was the Best Sound Card Creative labs ever produced. Part of the ultra high-performance Z-Series of Sound Blaster sound cards, the Sound Blaster Z is an ideal all-round solution for your PC gaming and entertainment needs.
For more details, read the rest of this web release note. The Sound Blaster Z has been updated with the Sound Blaster Command software so you can have access to all the latest industry-leading audio technologies, all in one place.
It was supported in Win98 thru Win-10 up until Creative Sound Blaster Driver for Windows 10 This download is a driver providing Microsoft® Windows® 10 support for Creative Sound Blaster® audio devices. Intel486dx33 wrote on, 16:21: The Sound Blaster Audigy 2zs was the Best Sound Card Creative labs ever produced.